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According to studies, MYC is overexpressed in 3050% of high-grade cancers and about 15% of breast tumors [42]

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It is important to note that use of medications such as beta blockers is contraindicated in these patients because they may result in syncope and increase the risk of death

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Glucose metabolism via the PPP is essential for the generation of NADPH that is required for reductive biosynthetic reactions such as those of cholesterol biosynthesis, bile acid synthesis, steroid hormone biosynthesis, and fatty acid synthesis

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