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First identified in human plasma, this endogenous peptide functions as a biological signaling molecule involved in cellular communication, tissue remodeling, and extracellular matrix regulation
Additionally, the UPS contributes to treatment resistance by degrading apoptosis-promoting factors and enhancing pro-survival signaling pathways, such as NF-B and PI3K/AKT
The system is designed to respond to velocity, and when velocity falls, so does its resolution
Eldredge, H
[DOI] [PMC free article] [PubMed] [Google Scholar] 31.Neri D., Steele E.M., Khandpur N., Cediel G., Zapata M.E., Rauber F., Marrn-Ponce J.A., Machado P., da Costa Louzada M.L., Andrade G.C., et al
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