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According to one study, about one in six patients experiences some form of local injection site reaction

At the same time, there has been ongoing public discussion about the regulatory status of peptides in the United States

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Some clinical studies have found elevated lactate levels (395, 396) in ME/CFS patient blood, cerebrospinal fluid, and muscles, suggesting there is reduced oxidative phosphorylation and a switch to anaerobic glycolysis (392, 397399)