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Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma

We defined index date as the date of first pharmacy fill of either GLP1-RA or DPP4i, and operated under the assumption that patients are taking the prescribed medication as directed

The protocols below draw from published studies and real-world athlete experience

This is to ensure that neither drug is causing problems and that the benefits of the medications outweigh any risks

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Set the dose to the smallest unit (usually 2 units on the dial)