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However, the embryonal rest hypothesis is not widely supported in current oncology, as most contemporary models emphasize the role of genetic and epigenetic alterations in adult stem or progenitor cells

In the present study, disrupted hepatic glutathione homeostasis was observed in mice chronically exposed to a HFD diet, which is characterized by GSH reduction and GSSG elevation

When SIRT3 removes acetyl groups from isocitrate dehydrogenase 2 (IDH2), more NADPH gets made in mitochondria

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