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The vascular resistance of the gingiva (GVR) was calculated as a ratio of MBP and GBF, and values were given in resistance (R) (mmHg/BPU)

TSH acts on the thyroid gland, promoting iodine uptake and production of thyroid hormones T 3 and T 4

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Introduction The concept of the leaky gut has received increasing attention in the lay press and also in the scientific literature of late due to its associations with numerous gastrointestinal (GI) and non-GI diseases such as irritable bowel syndrome, Alzheimers disease, asthma, type 2 diabetes, hepatic steatosis, and many others [1] to the point that dietary modifications, probiotics, and other interventions intended to increase gut integrity are recommended as treatments for a host of diseases [2, 3]

Similarly, CAR activation upregulates enzymes like CYP2B6 and transporters that contribute to the elimination of bilirubin and bile acid metabolites