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26,27 Drug Efficacy and Side Effects in Clinical Trials The first GLP-1RA that received FDA approval was put on the market in 2005 under the name exenatide

Its activation of three key hormone receptors makes it distinct from other weight loss medications and capable of achieving significant weight loss through improved glucose, insulin, and fat metabolism regulation

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Countless women and men experience weight loss resistance even after giving their lives a serious health makeover

It can worsen GI side effects, particularly nausea and bloating