Many patients begin their journey with medications and later move on to surgery when they need more permanent results
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The overall reduction in insulin secretion is also shown by reduced levels of C-peptide in the same studies
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Keywords MC4R deficiency , genetic obesity , GLP-1 receptor agonists , leptin-melanocortin pathway , weight management 0 1 INTRODUCTION Genetic obesity is broadly divided into syndromic obesity and non-syndromic obesity, both of which can be caused by monogenic, polygenic, or chromosomal abnormalities [1]
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