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[7] Another aspect is that MB, in high IV doses, can paradoxically cause methemoglobinemia because it can auto-oxidize at excessive concentrations

UV exposure can increase MMPs levels, which are responsible for ECM damage, including collagen, elastin, fibronectin and proteoglycans (54)

As such, plasma which was deproteinized prior to storage at 80 o C was thawed and further diluted 1:2.5 with assay buffer to produce a final dilution of 1:5 before assaying

doi: 10.1016/j.jconrel.2015.09.031 129 XuLFaruquFNLimYMLimKYLiam-OrRWaltersAAet al

Hydrogen-bond acceptor any atom with a large concentration of negative charge and a lone pair of electrons, such as N, O, or F

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