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Ozempic in Hollywood Although Ozempic is meant to treat type 2 diabetes and possibly weight loss for the obese with the approval of a doctor, many wealthy and famous people are taking Ozempic to lose a few extra pounds

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1 Introduction Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are a standard class of medications that are used to treat type 2 diabetes mellitus (T2DM) (Collins and Costello, 2024) These medications mimic the actions of a hormone naturally found in the intestines, glucagon-like peptide-1 (GLP-1), which regulates blood sugar levels by increasing insulin secretion and decreasing glucagon release

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DPP-4 not only cleaves and inactivates GLP-1, but also regulates the biological activities of GLP-2, a peptide known to enhance intestinal lipid absorption and/or chylomicron secretion (9, 4446)