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Maintenance Dosing Ranges and Individual Variation Maintenance doses for compounded semaglutide typically range from 1.0 mg to 2.0 mg weekly, though some patients achieve optimal results at intermediate doses like 1.5 mg

If you use stronger actives such as retinoids or exfoliating acids, apply them after LED or on alternate nights to reduce sensitivity

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This means there is no established pharmacological mechanism by which semaglutide would be expected to cause spotting or bleeding between periods

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