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Long-term use of L-carnitine accelerated the production of reactive oxygen species in the liver and blood in mice [62]

Ancillary analysis We used metformin as a control in the secondary analysis

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EMA (2012)

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Owing to the rapid increased prevalence of T2D and obesity, worldwide, and the robust prevailing weight reduction interventions to overcome the obesity-related morbidities, biliary tract diseases especially cholelithiasis represents an overwhelming complication in clinical practice [2]