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In the past two decades, several clinical trials targeted at the potential beneficial effects of CoQ10 in patients with PD have been conducted

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Water soluble vitamins, such as vitamin C, are rapidly eliminated from the body and their dietary levels need to be relatively high

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Additionally, B-CQDs administered intravenously localised in kidneys and lymph nodes, intraperitoneally in intestines, liver, heart, and spinal cord, and orally in liver, kidneys, and lymphatic tissue, with peak tissue accumulation occurring at 30 min, and rapid systemic clearance within 2 hours [159]