Su funcin principal es el transporte de cidos grasos a las mitocondrias, las "centrales energticas" de las clulas, donde las grasas se convierten en energa til para el organismo
We conducted a comprehensive literature search across databases, including PubMed and Web of Science, compiling data from clinical trials, case reports, and basic research studies published up to 2025, with a focus on the efficacy, safety, and mechanism of action of drugs such as liraglutide, semaglutide, and tirzepatide in patients with MC4R deficiency
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The brain doesnt respond to these drugs in a static wayit adapts. The team is also exploring molecular changes in peripheral tissues, such as liver, fat, and muscle, that may underlie the observed shift from fat to carbohydrate use during weight maintenance
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Ravi, P