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Glucagon administration also decreases hepatic triacylglycerol synthesis in rats [56] and stimulates hormone-sensitive lipase in human and rat white adipocytes to promote lipolysis and the release of NEFA [57, 58]

When the Whipple triad is documented, rule out nonhyperinsulinemic causes of hypoglycemia such as hypothyroidism, adrenal insufficiency, underlying organ dysfunction (ie, liver disease), and medications that cause hypoglycemia

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