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But due to the following factors, its levels deplete in the body: Stress Medication and Drugs Pollution Poor Diet Toxin buildup leading to increased oxidative stress Aging Keeping in mind the lifestyle of metrocities that includes poor diet, sleep and even habits like smoking and occasional alcohol consumption, Glutathione levels suffer in the process of upkeep and neutralising of free radicals
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however, vascular complications were not improved, most likely due to the excessive SOD-catalyzed formation of hydrogen peroxide, which causes endothelial damage (Rochette et al