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Your body cannot make vitamin B12 on its own, so it must come from food or supplementation

GLP-1 receptor agonists (semaglutide, liraglutide, dulaglutide) and the GIP/GLP-1 dual agonist tirzepatide were studied in STEP (NEJM 2021), SURMOUNT (NEJM 2022), and SURMOUNT-OSA (NEJM 2024)

Having the combination of two drugs increases efficacy Adults with migraines and obesity are good candidates for this weight-loss medication Side effects include dizziness, altered taste, and insomnia Contraindications include uncontrolled hypertension and coronary artery disease, hyperthyroidism, glaucoma, and sensitivity to stimulants Naltrexone-bupropion (Contrave) Combines an opioid receptor antagonist with an antidepressant Decrease cravings and appetite Side effects include nausea, constipation, and headache This medication should not be prescribed to a patient who has a seizure disorder or who takes opioids for chronic pain Setmelanotide (Imcivree) For chronic weight management in specific rare genetic disorders Requires confirmation through genetic testing Orlistat (Xenical and Alli) Inhibits the absorption of dietary fats Side effects include oily discharge and increased defecation Metformin Treats type 2 diabetes, and PCOS.It also helps significantly for weight management, particularly in those with insulin resistance

By understanding your genetic predispositions, you and your provider can time dose escalations to maximize efficacy while minimizing discomfort

Retatrutide x 10 Vials is supported by Janoshik third-party testing

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