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Metabolism GLP-1 gets rapidly metabolized in the circulation by dipeptidyl peptidase-4 (DPP-IV), resulting in a short plasma half-life of approximately 2 min [11]

Patients with previous GI intolerance to semaglutide face higher risk of similar issues with tirzepatide and may need extended titration periods or anti-nausea medications during transition

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Sertoli cells produce anti-Mllerian hormone (AMH) from the 7th week onward, inducing regression of Mllerian ducts [124]

Sertraline is a selective serotonin reuptake inhibitor (SSRI) used to treat depression, anxiety disorders, obsessive-compulsive disorder, and post-traumatic stress disorder