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Oral administration significantly reduces bioavailability due to enzymatic degradation in the digestive tract

In fact, administration of NOP receptor selective agonist UFP-112 during sensitization phase significantly reduced the AHR and lung eosinophilic infiltration in allergen-sensitized mice [44]

CONTRAINDICATIONS: PEG-MGF should not be used when there is any evidence of neoplastic activity

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NatureMDPI Long term human safety, pharmacokinetics, optimal dose, systemic exposure and oncologic risk signals are undefined (absence of evidence, not evidence of safety)