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Gastrointestinal Side Effects: GLP-1 medications often cause side effects like nausea, vomiting, or acid reflux [3]

Who qualifies: Generally BMI 30, or 27 with weight-related conditions (e.g., hypertension, insulin resistance)

Similarly, a study on women with PCOS found that about 44% experienced mild gastrointestinal effects when semaglutide was combined with metformin

While the results are not as dramatic as those from injectables, they may be safer and more sustainable

Remaining individuals were assigned to the exposure or control group based on which medication was first taken singularly in combination with metformin

For comparison, here is what other metabolic health investments cost monthly