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Importantly, exenatide-induced microbiota changes were functionally linked to inflammation and glycemic control, with enrichment of Akkermansia and taxa correlating negatively with inflammatory markers, and reductions in pathogenic bacteria correlating with improved metabolic profiles (43, 49)

A 2025 Kinsey study showed that 18% of respondents said their sexual desire had increased on GLP-1s while 16% said it had decreased

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The women who see the most dramatic transformations are the ones who stay consistent between months 3 and 6 after the initial adaptation is complete and the compounding effect kicks in

It was first identified in human plasma by Loren Pickart in 1973