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Relevant and reproducible animal models are critical for further studies of the side effects of GCs as well as novel ligands of glucocorticoid receptor (GR), in particular, selective glucocorticoid receptor agonists (SEGRAs)

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Compared with these strains, our multi-copy strains showed stronger tolerance to H 2 O 2 (anaerobic 3.5 mmol/L and aerobic 2.5 mmol/L), indicating marked improvement of antioxidant capacity