doi: 10.1007/s00018-020-03574-z 49 de KoningTJ
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In that regard, recent studies showed that FXR mediates an increased expression of Occludin, ZO-1, and claudin-1, all proteins involved in the formation of tight junctions, as well as defensins, involved in reducing the intestinal bacterial load [25]
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Oxidative stress occurs when unstable molecules, often called free radicals, accumulate faster than the body can clear them
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