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Anyone currently taking nitrate medications must strictly avoid NAC supplementation unless explicitly directed and closely monitored by a board-certified cardiologist

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But instead highlights that the delivery method could limit their potential benefits.Oral supplementation allows for controlled dosing and digestion-based absorption, which is why it is used in most clinical research

10.1210/en.2013-1556 Endocrinology 129 MullerF

Personalized dosing flexibility