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Perkins, Hao Chang, Wenfei Han, Ivan E
Retatrutide is called a triple G drug because it targets three different hormone receptors at the same time: GLP-1, GIP, and glucagon
GLP-1 also has an impact on the rate at which your stomach empties
It explains that slowed gastric emptying, suppressed hunger signals, and improved insulin sensitivity all reverse within days to weeks once dosing stops, because the body does not retain the medication effects on its own
N Engl J Med 384(11):9891002 Davies M, Frch L, Jeppesen OK et al (2021) Semaglutide 24 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial