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Dysregulation of the hypothalamicpituitaryadrenal axis increases central body fat accumulation in males affected by diabetes mellitus and late-onset hypogonadism

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If a patient is fortunate enough to seek out and obtain early medical attention (typically within 4 hours of the acute APAP ingestion), activated charcoal can be effective in limiting drug absorption, unless there are obvious contraindications, such as an unprotected airway or compromise of the gastrointestinal tract