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however, there is a lack of data supporting CV risk reduction in patients with clinical ASCVD

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doi:10.1007/s40265-021-01499-w 32

However, no effect of selenium supplementation on thyroid stimulating hormone, health-related quality of life or thyroid ultrasound was found in levothyroxine substitution-untreated individuals, and sporadic evaluation of clinically relevant outcomes in levothyroxine substitution-treated patients (108.5)