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Microdosing protocols might use 0.5mg or 1mg

The perfusion of 5-fluorouracil (5-FU), a common chemotherapeutic agent, through the vascular channel of the device, consistently exhibited expected hematotoxicity at clinically relevant low micromolar concentrations across six donors of CD34 + progenitor cells, demonstrating the reliability and relevance for toxicity testing

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But usually, [inaudible 00:10:19] the factors about 50 different symptoms of histamine, usually its in there in the background, as a bit of a bit of a problem, okay, so And then theres, obviously, weve got a genetics

Semin Cancer Biol (2018) 48:7890