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The radial or superficial spreading pattern is often seen in macular lesions, where clusters of pleomorphic melanocytes exhibiting nuclear atypia and hyperchromatism proliferate within the basal cell region of the epithelium

doi: 10.2174/157015913666160502153022

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At the molecular level, the major regulatory sites include membrane receptors, genes (gene expression regulation), mRNAs, and proteins

Niacinamide: a form of vitamin B3 that improves skin barrier function, evens tone, reduces fine lines, and strengthens cellular repair mechanisms

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