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1% achieving 20% WL respectively (Table 1) [45]

Remarkably, this inflammation-targeting SP@M restored osteoimmunology homeostasis, inhibited the activation of osteoclasts, protected bone formation, and promoted cartilage recovery in CIA mouse models in vivo (Fig

While higher doses (particularly 54 mg) showed some increase in gastrointestinal-related events, these remained mild to moderate in severity and did not result in treatment discontinuation

Glucocorticoids, secreted primarily by the adrenal glands, are important clinical drugs used to control pain and reduce inflammation in autoimmune diseases, neurological injury, cancer, and more

SREBP-1a-stimulated lipid synthesis is required for macrophage phagocytosis downstream of TLR4-directed mTORC1