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Those with primary adrenal insufficiency also need mineralocorticoid replacement with fludrocortisone

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doi: 10.1016/j.scitotenv.2018.06.356 24 GargN.BhandariP

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Importantly, the GM was determined to be more resilient to the lowered pH than the skin microbiota, likely because the GM are naturally exposed to acidic pH from gastric sections, and the researchers speculated that the dysbiosis they observed resulted from host physiological stress rather than directly from acute acidic exposure

Its a small peptide made up of three amino acids attached to a copper ion