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It has previously been suggested that mucosal immunity tends to be short-lived and that vaccines targeted to the mucosa may be less immunogenic at these sites [43], which are limitations that need to be overcome for efficacious mucosal-targeted vaccines

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The 10-year T-note now yields 4.56% - well off its peak but up 94 basis points from its recent low of 3.62% in September 2024

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