Viebahn GK, Khurana A, Freund L, et al
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In the context of mitohormesis, growing evidence suggests that an evolutionary hunter-gatherer dietary lifestyle aimed at balancing (1) minimally-processed, carbohydrate-restricted feeding periods (challenging, not excessive, stressor phases) with (2) intermittent fasting protocols (complete, not excessive, recovery phases) should be considered as a preventative and therapeutic strategy for neurodegenerative disorders
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GLP-1 users may not have such earnest study and medical knowledge thrust upon them
Finally, sirtuin 1 (SIRT1) has the potential to become a treatment strategy for T2DM