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370 ROS contribute to tumorigenesis through multiple processes, including causing oxidative DNA damage, genomic instability and inflammatory stress to drive malignant transformation, and acting as a messenger to regulate signaling pathways to support tumor initiation, development, and angiogenesis

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Clinical studies have also investigated the effect of topical L-carnitine on sebum production

Alpha lipoic acid is a skin-lightening agent that decreases the synthesis of melanin and treats hyperpigmentation