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Starting with a lower dose and working your way up gradually can help minimize the drama

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[7] Gregg, E

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Figure 1 The initial adhesion stage Reversible adhesion is usually initiated by the non-specific forces (van-der Waals, Brownian motion and electrostatic forces) haphazardly and then followed by the irreversible adhesion on the surface via a variety of different factors and mechanisms to form a complicated three-dimensional colony that is known as a biofilm (Dixit et al., 2019)