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The combined activation of these receptors resulted in synergistic effects in preclinical studies that were greater than what either hormone could accomplish on its own

Glycaemic control typically improves progressively during the first 36 months of treatment, with maximum HbA1c reductions generally observed by 4052 weeks

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Much of the foundational literature originates from a single research program, and all observations described here derive from controlled, non-clinical research conducted by third parties