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Variants in genes affecting liver metabolismparticularly those influencing cytochrome P450 enzyme activitydetermine how quickly your body breaks down warfarin and other anticoagulants

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GSTT ( n = 16) tended to perform 3.0 (0.53.5) adjustments per participant, whilst North Bristol ( n = 7) performed more adjustments, 4.0 (3.06.0)