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Candidacy for GLP-1 medications involves personal history screening (pancreatitis, thyroid cancer family history, diabetic retinopathy), while inositol is contraindicated primarily in individuals with specific phosphate wasting disorders

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However, translation of these findings to humans requires further investigation

"Two concentrations of topical tretinoin (retinoic acid) cause similar improvement of photoaging but different degrees of irritation: a double-blind, vehicle-controlled comparison of 0.1% and 0.025% tretinoin creams." Archives of dermatology 131.9 (1995): 1037-1044

10.3109/09513590.2015.1056730 66 ZhangH.MaY.CaoR.WangG.LiS.et al (2020)

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