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Yes, MOTS-c and 5-Amino-1MQ can be stacked because they operate through separate molecular pathways with complementary metabolic targets

free radicals include superoxide anion radical (O 2 - ), peroxyl (ROO), alkoxyl (RO), nitric oxide (NO), and hydroxyl radical (OH)

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The peptide undergoes rapid first-pass metabolism when absorbed, which is why bioavailability varies significantly by administration route

While GABAergic drugs (e.g., baclofen, bumetanide, homotaurine) show promise in preclinical models for ameliorating ASD-like behaviors, clinical translation remains limited by inconsistent efficacy and safety profiles