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Indeed, we found a similar mitochondrial response to pemetrexed treatment in three independent KRAS mutant non-small cell lung cancer cell lines (Extended Data Fig
ALA Primarily -linolenic acid DHA Docosahexaenoic acid EPA Eicosatetraenoic acid FAT Fatty acid translocase FATP4 Fatty acid transport protein 4 FFAs Free fatty acids GPx Peroxidase HDL High-density lipoprotein LDL Low-density lipoprotein ROS Reactive oxygen species 2-MAGs 2-Monoacylglycerols 5-MTHF 5-Methyltetrahydrofolate TG Triglycerides TrxR Thioredoxin reductase PUFAs Polyunsaturated fatty acids -3 PUFAs Omega-3 polyunsaturated fatty acids VLDLR Low-density lipoprotein receptor VTG Vitellogenin Fe Iron Cr Chromium I Iodine K Potassium Mn Manganese Na Sodium Se Selenium Zn Zinc Glossary References 1
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