Prescribing outside the licensed indications and doses constitutes off-label use, which requires prescribers to document their rationale, obtain informed consent, and provide appropriate monitoring
Tirzepatide reduces alcohol drinking and relapse-like behaviours in rodents
Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double-blind, placebo and active-comparator-controlled, parallel-group, phase 2 trial conducted in the USA
Safety considerations for GLP-1RA use Based on current data from clinical trials in MASLD and longer-term cohorts in T2DM and obesity, GLP-1RA is generally considered safe
GLP-1 Uses Under Investigation GLP-1s for Addiction Soon after GLP-1s became available for diabetes and then weight loss, users began anecdotally reporting fewer cravings for things like cigarettes and alcohol and less desire to engage in compulsive activities like shopping or gambling
"I feel like people don't really talk about the nasty sides of it, so I was kind of under the impression it was going to go well," she tells Yahoo
