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In a September 2004 article, the investigators presented evidence that selection for coat color has not only narrowed the CKCS gene pool, but also has influenced the spread of Chiari-like malformation (CM) and syringomyelia (SM) throughout the breed

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The latter typically occurs when reactive oxygen species, also known as harmful byproducts of metabolism, accumulate and affect DNA, proteins and lipids

Biomedicines 10 , 897 (2022)

Comienza con una revisin exhaustiva del cuerpo de literatura existente (y extensa), y contina adaptndola al objetivo de investigacin del estudio y al modelo utilizado en el experimento