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It suppresses NF-kB, which controls the expression of TNF-alpha along with dozens of other inflammatory mediators simultaneously

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Safety and Tolerability of the Hexadecapeptide AOD9604 in Humans, Stier H., Vos E., Kenley D., Journal (Journal of Endocrinology and Metabolism, Volume 3, Issues 12, 2013, Pages 715)

doi: 10.1177/0192623308329476

These dopaminergic interactions have expanded the range of research applications for BPC-157 beyond tissue repair into neuroscience and behavioral pharmacology, though it is important to note that all current evidence remains preclinical and should not be extrapolated to human applications

However, during aging, the M2 to M1 ratio decreases significantly [94]