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Aristolochic acid, mediated by p53, may limit ferroptosis in liver cancer to enhance tumor growth

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It is 15 amino acids long, which makes it large enough to have meaningful receptor interactions but small enough to synthesize cost-effectively

a low ratio decreases IL-12 secretion which favors a Th2 response pattern over Th1 (a condition typically associated with chronic inflammation), while an elevated ratio favors a Th1 response ( The glutaredoxin (Grx) system, another key player, operates in close association with the GSH pool and serves primarily to regulate protein thiol redox status through reversible de-glutathionylation

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