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Now a pair of independent clinical trials point to two possible methods for preventing weight regain: taking a daily oral GLP-1 drug called orforglipron or taking a supplement that contains a pasteurized strain of Akkermansia muciniphila bacteria

Available at: Lincoff AM, et al

This can support cardiovascular health, exercise capacity, and erectile function

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The overall inflated cost adds to limitation of access to these drugs in resource poor nations (124)

Because insurance companies tend to only cover prescriptions for their FDA-approved use, Blue Cross Blue Shield is more likely to cover Zepbound than Mounjaro for weight loss or sleep apnea, a recently FDA-approved use for Zepbound