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ISSN 2165-1736

World Obesity Federation

Side Effects Profile All three medications share common side effects, primarily gastrointestinal: Nausea (usually temporary, worst in first few weeks) Diarrhea or constipation Abdominal discomfort Reduced appetite (this is the goal, but can feel uncomfortable initially) The higher dose of Wegovy may cause more pronounced side effects initially, while Saxendas daily dosing can offer more stable blood levels with potentially fewer ups and downs

The risk of aspiration under anesthesia is real and potentially life-threatening

GLP-1 receptor agonists like semaglutide and tirzepatide work differently