glp 1 and sglt2

glp 1 and sglt2 GLP1 Receptor Agonists vs SGLT2-I in Preventing CKD in T2DM: An Interview – AJKD Blog SGLT2i and GLP-1 RA therapy

Name: glp 1 and sglt2 GLP1 Receptor Agonists vs SGLT2-I in Preventing CKD in T2DM: An Interview – AJKD Blog SGLT2i and GLP-1 RA therapy
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Description

GLP-1 (glucagon-like peptide-1) receptor agonists, such as semaglutide (Ozempic, Wegovy) or liraglutide (Saxenda), are medications originally developed for diabetes management but are also used for weight loss

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Diet, activity, other diabetes medicines, and glucose control can all influence weight changes

GLP-1, GIP and GCG (each at 1 nmol/l) enhanced GSIS by ~eightfold, ~fivefold and ~fourfold, respectively, whereas the triagonist (1 nmol/l) elicited an ~11-fold increase (Fig