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Mild tenderness or slight warmth that resolves within 24 hours also falls within expected responses

Common semaglutide side effects include nausea, vomiting, constipation, and diarrheamost mild and temporary during dose escalation

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Therapeutic peptides generally have very favorable safety profiles, they are short amino acid chains that the body recognizes as biological molecules rather than foreign compounds, and they are cleared naturally

This effect is directly linked to the medication's primary function

doi:10.1001/jama.2026.1030