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Elevated plasma long-chain acylcarnitine primarily reflects systemic fatty acid oxidation damage, with strong and stable detection signals that effectively capture systemic metabolic dysregulation [124, 155, 156]

Findings were generally similar across the weighted and propensity-score-matched analyses

Nausea (most common adverse event), vomiting, diarrhea, constipation, dyspepsia, and abdominal pain were the six most commonly reported events in the groups that received oral semaglutide compared to those who received placebo or comparators (Table 3) [39,40,41,42,43,44,45,46]

10.1002/jcb.28359 J

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Nat Reviews Cardiol