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doi:10.1007/s12178-025-09966-7 Peng Y, Lu M, Zhou Z, et al

Both NAC and L-NAC pretreatments decreased IL-8 levels in untreated control cells and 0.25 mM PQ-challenged cells, while L-NAC, but not NAC, was also able to significantly reduce levels of IL-8 following 1.0 mM PQ challenge

Both conditions produce facial bumps, but perioral dermatitis features smaller, more uniform papules with scaling and a distinctive distribution around the mouth

About three quarters of those calls involved children under 12